Dissecting Germ Cell Metabolism through Network Modeling
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چکیده
منابع مشابه
Dissecting Germ Cell Metabolism through Network Modeling
Metabolic pathways are increasingly postulated to be vital in programming cell fate, including stemness, differentiation, proliferation, and apoptosis. The commitment to meiosis is a critical fate decision for mammalian germ cells, and requires a metabolic derivative of vitamin A, retinoic acid (RA). Recent evidence showed that a pulse of RA is generated in the testis of male mice thereby trigg...
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1. EMBL/CRG Systems Biology Research Unit, Centre for Genomic Regulation (CRG), Barcelona, Spain 2. Universitat Pompeu Fabra, Barcelona, Spain 3. Theoretical Biophysics, Humboldt-Universität zu Berlin, Berlin, Germany 4. Synthetic and Systems Biology Group, Helmholtz Center for Infection Research (HZI), Braunschweig, Germany 5. Department of Experimental and Health Sciences, Pompeu Fabra Univer...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2015
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0137607